| No | Size | Price | Availability | |
| YRP08676-01 | 50ul | 1500.00 | In Stock |  |
| YRP08676-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 64210 |
| Isotype: | IgG | Swiss Prot: | Q96T76 |
| purity: | Purified by Protein A. |
| Background: |
| Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human MMS 19 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
