| No | Size | Price | Availability | |
| YRP08542-01 | 50ul | 1500.00 | In Stock |  |
| YRP08542-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6916 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Thymidylate synthase (TS) is an intracellular enzyme critical for de novo synthesis of DNA. In cancer, expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Thymidylate synthase/TS |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | d TMP synthase, EC 2.1.1.45, HsT422, MGC88736, Thymidylate synthase, thymidylate synthetase, TMS, TS, TSase, TYMS, TYMS protein, Tyms thymidylate synthetase, TYSY_HUMAN . |
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