RAB40A Rabbit Polyclonal Antibody
No Size Price Availability  
YRP08371-01 50ul 1500.00 In Stock
YRP08371-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 142684
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 40A, Rab 40B and Rab 40C each contain one SOCS box domain and are members of the Rab subfamily of GTPases. Localized to the cytoplasmic side of the cell membrane, Rab 40A, Rab 40B and Rab 40C are thought to function as substrate-recognition components of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that functions to mediate the degradation of target proteins.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human RAB40A
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Protein Rar 2, RAB40A, member RAS oncogene family, Rar 2, RAR2A, Ras related protein Rab 40A, SOCS box containing protein RAR2A, RB40A_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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