Source: | Rabbit | Gene Id: | 342977 |
Isotype: | IgG | Swiss Prot: | P60323 |
purity: | Purified by Protein A. |
Background: |
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
|
Immunogen | KLH conjugated synthetic peptide derived from human Nanos3 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | NOS3, NANOS1L, Nanos homolog 3, NOS-3, NANOS3 |
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