| No | Size | Price | Availability | |
| YRP07867-01 | 50ul | 1500.00 | In Stock |  |
| YRP07867-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10447 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| ILEI is a 227 amino acid, ubiquitously expressed protein containing an amino-terminal signal peptide. Elevated levels of ILEI translation are observed in oncogenic, Ras-transformed mammary epithelial cells and epithelial to mesenchymal transition (Emt) as well as tumor growth and metastasis. Also, overexpression of ILEI results in loss of ZO-1, a protein involved in tight junctions, and expression of cytoplasmic E-cadherin, which has been shown to influence loss of polarity and invasiveness. Due to this evidence, it is suspected that ILEI cooperates with oncogenic Ras to cause TGF∫-independent Emt and its overexpression is correlated with the invasion, metastasis and survival in a variety of cancers. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human FAM3C |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Fam3c, FAM3C_HUMAN, family with sequence similarity 3, member C, GS3786;ILEI, Interleukin-like EMT inducer, Predicted osteoblast protein, Protein FAM3C. |
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