| No | Size | Price | Availability | |
| YRP07761-01 | 50ul | 1500.00 | In Stock |  |
| YRP07761-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 55200 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human MyoGEF |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Myosin interacting guanine nucleotide exchange factor, PH domain containing family G member 6, Pleckstrin homology domain containing family G with RhoGef domain member 6, Pleckstrin homology domain-containing family G member 6, PLEKHG6；PKHG6_HUMAN。 |
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