
| Source: | Rabbit | Gene Id: | 56739 |
| Isotype: | IgG | Swiss Prot: | Q8C5S7 |
| purity: | Purified by Protein A. |
| Background: |
| Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. |
| Reactivity | Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from mouse REC8 around the phosphorylation site of Ser251 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | mrec, Rec8L1, Meiotic recombination protein REC8 homolog, Cohesin Rec8p, Rec8, Mei8 |
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