Source: | Rabbit | Gene Id: | 55328 |
Isotype: | IgG | Swiss Prot: | Q5VYX0 |
purity: | Purified by Protein A. |
Background: |
Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
|
Immunogen | KLH conjugated synthetic peptide derived from human Renalase |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | C10orf59, RENALASE, Monoamine oxidase-C, MAO-C, alpha-NAD(P)H oxidase/anomerase, RNLS |
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