Source: | Rabbit | Gene Id: | 23164 |
Isotype: | IgG | Swiss Prot: | Q6WCQ1 |
purity: | Purified by Protein A. |
Background: |
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. |
Reactivity | Human |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human RIP3 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | MRIP, RIP3, M-RIP, RHOIP3, p116Rip, Myosin phosphatase Rho-interacting protein, Rho-interacting protein 3, MPRIP, KIAA0864 |
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