Source: | Rabbit | Gene Id: | 7128 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | Listeria induced, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, ABIN-3 beta, FLJ21162, LIND, Listeria induced gene protein, TNFAIP3 interacting protein 3, TNFAIP3-interacting protein 3 beta, TNIP3, TNIP3 beta, TNIP3_HUMAN. |
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