SPANX Rabbit Polyclonal Antibody
No Size Price Availability  
YRP07017-01 50ul 1500.00 In Stock
YRP07017-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 30014
Isotype: IgG Swiss Prot: Q9NS26
purity: Purified by Protein A.
Background:
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008]
Reactivity Human
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human SPANXA
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym NAP-X, SPANX, CT11.1, SPAN-X, SPAN-Xa, SPAN-Xb, SPANX-A, Sperm protein associated with the nucleus on the X chromosome A, Cancer/testis antigen 11.1, Nuclear-associated protein SPAN-Xa, SPANX family member A, SPANXA1, SPANXA
This product is for research use only, not for diagnostic or therapeutic use!

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