| No | Size | Price | Availability | |
| YRP07012-01 | 50ul | 1500.00 | In Stock |  |
| YRP07012-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 54894 |
| Isotype: | IgG | Swiss Prot: | Q68DV7 |
| purity: | Purified by Protein A. |
| Background: |
| E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human RNF43 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | URCC, RNF124, E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RNF43 |
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