| No | Size | Price | Availability | |
| YRP06907-01 | 50ul | 1500.00 | In Stock |  |
| YRP06907-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5905 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq, Jul 2008]. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human RanGAP1 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Fug 1, Fug-1, Fug1, KIAA1835, RAGP1_HUMAN, Ran 1, RAN GTPase activating protein 1, RAN GTPase-activating protein 1, Ran-1, Ran1, RANGAP 1, RanGAP1, RANGAP1, SD antibody Segregation distorter homolog, Segregation distortion. |
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