| No | Size | Price | Availability | |
| YRP06784P-01 | 50ul | 1500.00 | In Stock |  |
| YRP06784P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4293 |
| Isotype: | IgG | Swiss Prot: | P80192 |
| purity: | Purified by Protein A. |
| Background: |
| Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human MAP3K9 around the phosphorylation site of Thr312 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | MLK1, MEKK9, PRKE1, Mitogen-activated protein kinase kinase kinase 9, Mixed lineage kinase 1, MAP3K9 |
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