| Source: | Rabbit | Gene Id: | 9538 | 
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. | 
| Background: | 
| This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human TP53I8/EI24 | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | Ei24, EI24_HUMAN, EPG4, Etoposide induced 2.4 mRNA, Etoposide-induced protein 2.4 homolog, p53-induced gene 8 protein, PIG8, TP53I8, Tumor protein p53 inducible protein 8. | 
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