| No | Size | Price | Availability | |
| YRP06593-01 | 50ul | 1500.00 | In Stock |  |
| YRP06593-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 81794 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ADAMTS10 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | A disintegrin and metalloproteinase with thrombospondin mots 10, A disintegrin like and metalloprotease reprolysin type with thrombospondin type 1 mot, 10, ADAM metallopeptidase with thrombospondin type 1 mot 10, ADAM TS10, EC 3.4.24, WMS, ATS10_HUMAN. |
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