Source: | Rabbit | Gene Id: | 101185 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from mouse POT1 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | hPot 1, hPot1, OT 1, POT1, POT1 like telomere end-binding protein, POT1 protection of telomeres 1 homolog, POT1-like telomere end-binding protein, POTE1_HUMAN, Protection of telomeres 1, Protection of telomeres protein 1. |
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