Source: | Rabbit | Gene Id: | 55851 |
Isotype: | IgG | Swiss Prot: | Q9NZ42 |
purity: | Purified by Protein A. |
Background: |
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. |
Reactivity | Human, Mouse, Rat |
Tested applications | IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human PEN2 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN |
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