Source: | Rabbit | Gene Id: | 118 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser726 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | alpha Adducinphospho S726, beta Adducin. Gamma Adducin, ADD 1, ADD A, ADD1, ADD1 protein, ADDA, ADDA_HUMAN, Adducin 1 alpha, Adducin 1 alpha, Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte adducin subunit alpha; |
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