HRAS+KRAS Rabbit Polyclonal Antibody
No Size Price Availability  
YRP06170-01 50ul 1500.00 In Stock
YRP06170-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3265
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human HRAS+KRAS
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym p21ras, Transforming protein p21, GTPase HRas, GTPase KRas, HRas, HRAS1, KRas, KRAS2, RASH, RASK, RASH_HUMAN, RASK_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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