| No | Size | Price | Availability | |
| YRP06117-01 | 50ul | 1500.00 | In Stock |  |
| YRP06117-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6764 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ST5/DENND2B |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | DENND2B, DENN domain containing protein 2B, HeLa tumor suppression 1, DENN domain-containing protein 2B, DENN/MADD domain containing 2B, DENND2B, HTS1, p126, ST 5, ST5, ST5_HUMAN, Suppression of tumorigenicity 5, Suppression of tumorigenicity 5 protein. |
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