Source: | Rabbit | Gene Id: | 94 |
Isotype: | IgG | Swiss Prot: | P37023 |
purity: | Purified by Protein A. |
Background: |
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human ALK1 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, TGF-B superfamily receptor type I, ACVRL1 |
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