DAB2 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP06004-01 50ul 1500.00 In Stock
YRP06004-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 1601
Isotype: IgG Swiss Prot: P98082
purity: Purified by Protein A.
Background:
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human DAB2
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym DOC2, DOC-2, Disabled homolog 2, Differentially-expressed protein 2, DAB2
This product is for research use only, not for diagnostic or therapeutic use!

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