Phospho-p107(Thr369) Rabbit Polyclonal Antibody
No Size Price Availability  
YRP05986P-01 50ul 1500.00 In Stock
YRP05986P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5933
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic phosphopeptide derived from human p107 around the phosphorylation site of Thr369
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym RBL1phospho T369, 107 kDa retinoblastoma-associated protein, Cellular protein 107, Cellular protein p107, CP107, MGC40006, p107, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, retinoblastoma-like 1 p107, Retinoblastoma-like protein 1.
This product is for research use only, not for diagnostic or therapeutic use!

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