SERINC3 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP05947-01 50ul 1500.00 In Stock
YRP05947-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 10955
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human SERINC3
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym TMS 1, TMS-1, AIGP1, DF33, SBBI99, serine incorporator 3, TDE, TDE1, Tumor dferentially expressed protein 1, SERC3_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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