| No | Size | Price | Availability | |
| YRP05923-01 | 50ul | 1500.00 | In Stock |  |
| YRP05923-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 27329 |
| Isotype: | IgG | Swiss Prot: | Q9Y5C1 |
| purity: | Purified by Protein A. |
| Background: |
| Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | ANL3, ANG-5, FHBL2, ANGPT5, Angiopoietin-related protein 3, Angiopoietin-5, Angiopoietin-like protein 3, ANGPTL3, UNQ153/PRO179 |
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