| No | Size | Price | Availability | |
| YRP05875-01 | 50ul | 1500.00 | In Stock |  |
| YRP05875-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5653 |
| Isotype: | IgG | Swiss Prot: | Q92876 |
| purity: | Purified by Protein A. |
| Background: |
| Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis. |
| Reactivity | Human, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human KLK6 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | hK6, Bssp, Klk7, SP59, PRSS9, PRSS18, Kallikrein-6, Neurosin, Protease M, Serine protease 18, Serine protease 9, Zyme, KLK6 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
