Source: | Rabbit | Gene Id: | 18761 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. |
Reactivity | Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic phosphopeptide derived from mouse PRKCQ around the phosphorylation site of Ser695 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | PRKCQphospho S695, PKC??Ser695, PKC thetaphospho S695, PKC 0, PRKCQ, PKC0, Prkcq, PRKCT, Protein kinase C theta, Protein kinase C theta type, Protein Kinase Ctheta, KPCT_HUMAN, nPKC theta, nPKC-theta, nPKCtheta. |
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