| No | Size | Price | Availability | |
| YRP00993-01 | 50ul | 1500.00 | In Stock |  |
| YRP00993-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7037 |
| Isotype: | IgG | Swiss Prot: | P02786 |
| purity: | Purified by Protein A. |
| Background: |
| Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Transferrin receptor |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC |
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