| No | Size | Price | Availability | |
| YRP05580P-01 | 50ul | 1500.00 | In Stock |  |
| YRP05580P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5563 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human PRKAA2 around the phosphorylation site of Ser173 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | AMPK alpha 2 phospho Ser173, AMPK alpha 2 phospho S173, PRKAA2phospho S173, p-AMPK alpha 2 Ser173, p-AMPK alpha 2 S173, AMPK 2, AMPK2, AMPKalpha2, PRKAA 2, PRKAA, PRKAA2, Protein kinase AMP activated alpha 2 catalytic subunit. |
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