| No | Size | Price | Availability | |
| YRP05365P-01 | 50ul | 1500.00 | In Stock |  |
| YRP05365P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3014 |
| Isotype: | IgG | Swiss Prot: | P16104 |
| purity: | Purified by Protein A. |
| Background: |
| Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Histone H2AX around the phosphorylation site of Tyr143 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | H2AX, H2A.X, H2A/X, Histone H2AX, Histone H2A.X, H2AFX |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
