Phospho-CREB-1(Ser142) Rabbit Polyclonal Antibody
No Size Price Availability  
YRP05274P-01 50ul 1500.00 In Stock
YRP05274P-01 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 1385
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2, ATF-1,ATF-2,ATF-3and ATF-4. these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains. Although each of the ATF/CREB proteins bind CREs in their homodimeric form, in cerain instances they also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), which may reprecent a CREB co-activator.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser142 [DL(p-S)SD]
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Active transcription factor CREB, cAMP response element binding protein, cAMP responsive element binding protein 1, CREB1, CREB 1, CREB1, MGC9284, Transactivator protein, CREB.
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us