Phospho-Caspase-9 (Ser196) Rabbit Polyclonal Antibody
No Size Price Availability  
YRP05246P-01 50ul 1500.00 In Stock
YRP05246P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 842
Isotype: IgG Swiss Prot: P55211
purity: Purified by Protein A.
Background:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Reactivity Human
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9
This product is for research use only, not for diagnostic or therapeutic use!

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