Lamin B Receptor Rabbit Polyclonal Antibody
No Size Price Availability  
YRP05086-01 50ul 1500.00 In Stock
YRP05086-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3930
Isotype: IgG Swiss Prot: Q14739
purity: Purified by Protein A.
Background:
Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Lamin B Receptor
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR
This product is for research use only, not for diagnostic or therapeutic use!

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