

| Source: | Rabbit | Gene Id: | 632 | 
| Isotype: | IgG | Swiss Prot: | P02818 | 
| purity: | Purified by Protein A. | 
| Background: | 
| Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                    
                                     IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human Osteocalcin | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, BGLAP | 
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