

| Source: | Rabbit | Gene Id: | 5788 | 
| Isotype: | IgG | Swiss Prot: | P08575 | 
| purity: | Purified by Protein A. | 
| Background: | 
| Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). | 
| Reactivity | Human | 
| Tested applications | WB FC IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    FC 1:20-1:100 
                                    
                                    
                                 | 
                            
| Immunogen | KLH conjugated synthetic peptide derived from human CD45/B220 | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, PTPRC | 
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