Source: | Rabbit | Gene Id: | 19264 |
Isotype: | IgG | Swiss Prot: | P06800 |
purity: | Purified by Protein A. |
Background: |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity. |
Reactivity | Mouse |
Tested applications | WB FC IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
Immunogen | KLH conjugated synthetic peptide derived from mouse CD45 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | loc, B220, Cd45, L-CA, Ly-5, T200, CD45R, Lyt-4, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, Lymphocyte antigen 5, Ptprc |
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