
| Source: | Rabbit | Gene Id: | 9476 | 
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. | 
| Background: | 
| Napsin A is an aspartic proteinase that belongs to the peptidase A1 family and plays a role in pneumocyte surfactant processing. It is a 420-amino acid polypeptide consisting of a 24-residue signal peptide, a 40-amino acid propart, the mature enzyme of 336 amino acids, and a C-terminal extension of 18 residues. The mature Napsin A protein contains 3 predicted disulfide bonds, 3 potential N-linked oligosaccharide attachment sites, an RGD motif, a recognition motif for integrin binding, in the C terminus, immediately before a 4-amino acid insert that is unique to aspartic proteinases. Highest levels of Napsin A have been detected in adult lung (type II pneumocytes), fetal lung, and kidney tissues. Napsin A is also expressed at lower levels in adult spleen and at very low levels in peripheral blood leukocytes. Human napsin A shares 72.6% sequence identity with the mouse homolog. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
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| Immunogen | KLH conjugated synthetic peptide derived from human NAPSIN A | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | NAPSIN A, Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, Kidney derived aspartic protease like protein, NAP1, NAPA, Napsa, NAPSA_HUMAN, Napsin 1, napsin A aspartic peptidase, Napsin A precursor, Napsin-1, Napsin-A, Pronapsin A, SNAPA, TA01/TA02. | 
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