Taurine Rabbit Polyclonal Antibody
No Size Price Availability  
YRP04565-01 50ul 1500.00 In Stock
YRP04565-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id:
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
Taurine is conjugated via its amino terminal group with the bile acids chenodeoxycholic acid and cholic acid to form the bile salts sodium taurochenodeoxycholate and sodium taurocholate. The low pKa (1.5) of taurine's sulfonic acid group ensures that this moiety is negatively charged in the pH ranges normally found in the intestinal tract and thus improves the surfactant properties of the cholic acid conjugate. Taurine has also been implicated in a wide array of other physiological phenomena including inhibitory neurotransmission, long-term potentiation in the striatum/hippocampus, membrane stabilization, feedback inhibition of neutrophil/macrophage respiratory bursts, adipose tissue regulation and calcium homeostasis. The evidence for these claims, when compared against that reported for taurine's role in bile acid synthesis and osmoregulation, is relatively poor. Premature born infants who lack the enzymes needed to convert cystathione to cysteine may become deficient in taurine. Thus, taurine is a dietary essential nutrient in these individuals. Many therapeutic applications of taurine have been investigated. Some conditions that taurine might be useful in treating include: cardiovascular diseases, hypercholesterolemia, epilepsy and other seizure disorders, macular degeneration, Alzheimer's disease, hepatic disorders, alcoholism, and cystic fibrosis. Recent studies show that taurine supplements taken by mice on a high-fat diet reduced their overall weight. Studies have yet to be done on the effect of taurine on obesity in humans.
Reactivity Others (Taurine)
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated to Taurine
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym 2 aminoethanesulfonic acid, Taurine
This product is for research use only, not for diagnostic or therapeutic use!

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