Source: | Rabbit | Gene Id: | 55602 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
CARF was first cloned as a novel binding partner of ARF from a yeast interactive screen. CARF and ARF colocalize in the perinucleolar region and have a collaborative function. In the nucleoplasm, CARF interacts with p53 and enhances its function. The p53 downregulates CARF in a negative feedback regulatory loop and may also involve p53 antagonist HDM2. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human CARF |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | Calcium response factor, CARF, CDKN2A interacting protein, CDKN2AIP, ALS2CR8, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, CaRF, Testis development protein NYD-SP24, AL2S8_HUMAN. |
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