Source: | Rabbit | Gene Id: | 51107 |
Isotype: | IgG | Swiss Prot: | Q96BI3 |
purity: | Purified by Protein A. |
Background: |
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human APH1a |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | APH-1, APH-1A, CGI-78, 6530402N02Rik, Gamma-secretase subunit APH-1A, Aph-1alpha, Presenilin-stabilization factor, APH1A, PSF, UNQ579/PRO1141 |
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