| No | Size | Price | Availability | |
| YRP04256-01 | 50ul | 1500.00 | In Stock |  |
| YRP04256-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 112398 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| PHD1 catalyzes the posttranslational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins and hydroxylates HIF-1 alpha at Pro-402 and Pro-564, and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitylation complex. It may play a role in cell growth regulation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human PHD1/prolyl hydroxylase |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Egl nine homolog 2, prolyl hydroxylase;EGLN 2, EGLN2, EIT 6, EIT6, H P4H 1, H PH1, HPH1, HPH 3, HPH3, P4H1, PHD 1, PHD1, EGL nine C.elegans homolog 2, EGLN2_HUMAN. |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
