| No | Size | Price | Availability | |
| YRP04250-01 | 50ul | 1500.00 | In Stock |  |
| YRP04250-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9361 |
| Isotype: | IgG | Swiss Prot: | P36776 |
| purity: | Purified by Protein A. |
| Background: |
| ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human LONP1 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | LON, LONP, PIM1, hLON, LonHS, PRSS15, Lon protease homolog, mitochondrial, Lon protease-like protein, Mitochondrial ATP-dependent protease Lon, Serine protease 15, LONP1 |
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