| Source: | Rabbit | Gene Id: | 875 | 
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. | 
| Background: | 
| The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010]. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC IF | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | / | 
| Recommended Dilutions | 
                                     WB 1:100-1:1000 
                                    IHC 1:100-1:500 
                                    IF 1:50-1:200 
                                    
                                    
                                    
                                    
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| Immunogen | KLH conjugated synthetic peptide derived from human CBS/HIP4 | 
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months | 
| Synonym | Beta thionase, Beta-thionase, Cbs, CBS_HUMAN, Cystathionine beta synthase, Cystathionine beta-synthase, HIP 4, HIP4, Methylcysteine synthase, Serine sulfhydrase. | 
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