| No | Size | Price | Availability | |
| YRP04008P-01 | 50ul | 1500.00 | In Stock |  |
| YRP04008P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1981 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Summary: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq]. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human eIF4G around the phosphorylation site of ser1185 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | e4G Ser1185, e4G S1185, p-e4G Ser1185, p-e4G S1185, e 4 gamma 1, e 4G 1, e 4G1, E4 gamma, E4F, E4G, E4GI, Eukaryotic translation initiation factor 4 gamma 1, p220, DKFZp686A1451, e-4-gamma 1, e-4G 1, e-4G1, E4G-I, 4G1_HUMAN. |
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