Legumain Rabbit Polyclonal Antibody
No Size Price Availability  
YRP03912-01 50ul 1500.00 In Stock
YRP03912-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5641
Isotype: IgG Swiss Prot: Q99538
purity: Purified by Protein A.
Background:
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Legumain
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym AEP, LGMN1, PRSC1, Legumain, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN
This product is for research use only, not for diagnostic or therapeutic use!

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