Source: | Rabbit | Gene Id: | 5641 |
Isotype: | IgG | Swiss Prot: | Q99538 |
purity: | Purified by Protein A. |
Background: |
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human Legumain |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | AEP, LGMN1, PRSC1, Legumain, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.