| No | Size | Price | Availability | |
| YRP03626-01 | 50ul | 1500.00 | In Stock |  |
| YRP03626-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1977 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human eIF4E |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | E4F, e-4E, e 4E, CBP, e 4F 25 kDa subunit, CBP, e 4E, e 4F 25 kDa subunit, E 4F, E4E1, E4EL1, E4F, Eukaryotic Translation Initiation Factor 4 E, Eukaryotic translation initiation factor 4E like 1, Messanger RNA Cap Binding Protein e 4E. |
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