| No | Size | Price | Availability | |
| YRP03592-01 | 50ul | 1500.00 | In Stock |  |
| YRP03592-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8711 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Tnk1 is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Tnk1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Tnk1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Tnk1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human TNK1 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | CD38 negative kinase 1, EC 2.7.10.2 antibody Kinase of embryonic stem cells, Kos 1, Kos1, MGC46193, Non receptor tyrosine protein kinase TNK 1, Non receptor tyrosine protein kinase TNK1, Tnk 1, Tyrosine kinase non receptor 1. |
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