SMC1 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP03573-01 50ul 1500.00 In Stock
YRP03573-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 8243
Isotype: IgG Swiss Prot: Q14683
purity: Purified by Protein A.
Background:
Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human SMC1
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym SMC1, SMCB, CDLS2, SB1.8, SMC1L1, DXS423E, SMC1alpha, Structural maintenance of chromosomes protein 1A, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1A, KIAA0178
This product is for research use only, not for diagnostic or therapeutic use!

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