| No | Size | Price | Availability | |
| YRP03345P-01 | 50ul | 1500.00 | In Stock |  |
| YRP03345P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5331 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser537 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | PLC beta3 Ser537, Phospholipase C beta 3, Phospholipase C beta 3 phosphatidylinositol specic, PLC beta 3, PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3, Phosphoinositide phospholipase C, PLCB3_HUMAN. |
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